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Leen Beller

Leen Beller

  • Life Sciences
  • Dutch Patent Attorney
  • Associate

After studying Biomedical Sciences at KU Leuven, Leen started her PhD at the REGA institute of the KU Leuven in 2015. During five years, she investigated how the gut flora (gut microbiome) of healthy infants develops in their first year of life.

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She specialized in the many aspects of microbiology and genomics, but also in bioinformatics and biostatistics.

Working experience

  • Patent Attorney, V.O. (March 2025)
  • Trainee Patent Attorney, V.O. (2021-2025)
  • PhD student, Rega Institute KU Leuven (2015-2021)

Education

  • PhD in Biomedical Sciences, KU Leuven (2020)
  • MSc in Biomedical Sciences, KU Leuven (2015)
  • BSc in Biomedical Sciences, KU Leuven (2013)

Publications

  • Conceição-Neto, N., Zeller, M., Lefrère, H., De Bruyn, P., Beller, L., Deboutte, W., Yinda, C. K., Lavigne, R., Maes, P., Ranst, M. Van, Heylen, E. & Matthijnssens, J. Modular approach to customise sample preparation procedures for viral metagenomics: A reproducible protocol for virome analysis. Sci. Rep. 5, 16532 (2015).
  • Yinda, C. K., Zeller, M., Conceição-Neto, N., Maes, P., Deboutte, W., Beller, L., Heylen, E., Ghogomu, S. M., Van Ranst, M. & Matthijnssens, J. Novel highly divergent reassortant bat rotaviruses in Cameroon, without evidence of zoonosis. Sci. Rep. 6, 34209 (2016).
  • Yinda, C. K., Ghogomu, S. M., Conceição-Neto, N., Beller, L., Deboutte, W., Vanhulle, E., Maes, P., Van Ranst, M. & Matthijnssens, J. Cameroonian fruit bats harbor divergent viruses, including rotavirus H, bastroviruses, and picobirnaviruses using an alternative genetic code. Virus Evol. 4, vey008 (2018).
  • Theuns, S., Vanmechelen, B., Bernaert, Q., Deboutte, W., Vandenhole, M., Beller, L., Matthijnssens, J., Maes, P. & Nauwynck, H. J. Nanopore sequencing as a revolutionary diagnostic tool for porcine viral enteric disease complexes identifies porcine kobuvirus as an important enteric virus. Sci. Rep. 8, 9830 (2018).
  • Vanmechelen, B., Bletsa, M., Laenen, L., Lopes, A. R., Vergote, V., Beller, L., Deboutte, W., Korva, M., Avšič Županc, T., Goüy de Bellocq, J., Gryseels, S., Leirs, H., Lemey, P., Vrancken, B. & Maes, P. Discovery and genome characterization of three new Jeilongviruses, a lineage of paramyxoviruses characterized by their unique membrane proteins. BMC Genomics 19, 617 (2018).
  • Yinda, C. K., Vanhulle, E., Conceição-Neto, N., Beller, L., Deboutte, W., Shi, C., Ghogomu, S. M., Maes, P., Van Ranst, M. & Matthijnssens, J. Gut Virome Analysis of Cameroonians Reveals High Diversity of Enteric Viruses, Including Potential Interspecies Transmitted Viruses. mSphere 4, (2019).
  • Beller, L. & Matthijnssens, J. What is (not) known about the dynamics of the human gut virome in health and disease. Curr. Opin. Virol. 37, 52–57 (2019).
  • Shi, C., Beller, L., Deboutte, W., Yinda, K. C., Delang, L., Vega-Rúa, A., Failloux, A.-B. & Matthijnssens, J. Stable distinct core eukaryotic viromes in different mosquito species from Guadeloupe, using single mosquito viral metagenomics. Microbiome 7, 121 (2019).
  • Wollants, E., Beller, L., Beuselinck, K., Bloemen, M., Lagrou, K., Reynders, M. & Van Ranst, M. A decade of enterovirus genetic diversity in Belgium. J. Clin. Virol. 121, 104205 (2019).
  • Deboutte, W., Beller, L., Yinda, C. K., Maes, P., de Graaf, D. C. & Matthijnssens, J. Honey-bee–associated prokaryotic viral communities reveal wide viral diversity and a profound metabolic coding potential. Proc. Natl. Acad. Sci. U. S. A. 117, 10511–10519 (2020).
  • Thijssen, M., Tacke, F., Beller, L., Deboutte, W., Yinda, K. C., Nevens, F., Laleman, W., Van Ranst, M. & Pourkarim, M. R. Clinical relevance of plasma virome dynamics in liver transplant recipients. EBioMedicine 60, 103009 (2020).
  • Simsek, C., Corman, V. M., Everling, H. U., Lukashev, A. N., Rasche, A., Maganga, G. D., Binger, T., Jansen, D., Beller, L., Deboutte, W., Gloza-Rausch, F., Seebens-Hoyer, A., Yordanov, S., Sylverken, A., Oppong, S., Sarkodie, Y. A., Vallo, P., Leroy, E. M., Bourgarel, M., Yinda, K. C., Van Ranst, M., Drosten, C., Drexler, J. F. & Matthijnssens, J. At least seven distinct rotavirus genotype constellations in bats with evidence of reassortment and zoonotic transmissions. MBio 12, (2021).

Languages

  • Dutch (native)
  • English (fluent)
  • French (basic)

 

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News

Remembering Mark Einerhand

It is with great sadness that we have received the news of the passing, on 14 April, of our dear colleague and partner, Mark Einerhand. Mark joined V.O. in 1998 and has made a lasting contribution to the success of our firm.Continue reading

Validation agreement with Laos in force

As of 1 April 2025, the validation agreement between the European Patent Office (EPO) and the Lao PDR has entered into force. As a result, granted European patents can now be validated in Laos according to that country’s national patent law.Continue reading

Column: Can I only get a patent for breakthrough inventions?

In my work as a patent attorney, I notice that there is a lot of confusion among inventors about the requirements for a patent. Many inventors seem to be under the impression that patents are only granted for “breakthrough inventions”, such as the mRNA technology underlying – among others – the Covid vaccines, or novel […]Continue reading

Events

NL Startup Competition 2025

3089 JB Rotterdam, Netherlands

In April and May the second edition of NL Startup Competition, organized by Erasmus Enterprises, will take place. An extraordinary opportunity for innovative talents who take up the challenge to pitch their startup for prize money, a valuable network and knowledge.

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Knowledge for Growth 2025

Flanders Meeting & Convention Center Antwerp, Koningin Astridplein, Antwerpen, Belgium

The crème de la crème of the Belgian life sciences community is present at flanders.bio's annual Knowledge for Growth conference, which brings together decision-makers from the biotech, pharma and medtech, agriculture and chemical industries, as well as investors, universities, top research institutions, policy makers and competence providers.

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Grand Finale TU Delft Impact Contest 2025

YES!Delft, Molengraaffsingel 12, Delft

Each year, the TU Delft Impact Contest offers students the opportunity to further develop their own ingenious ideas, prototypes and research projects into business plans. The main goal and mission is to challenge students to come up with great innovative solutions to societal problems out-of-the-box, and translate them into real products and business plans.

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