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Leen Beller

Leen Beller

  • Life Sciences
  • Trainee Patent Attorney

After studying Biomedical Sciences at KU Leuven, Leen started her PhD at the REGA institute of the KU Leuven in 2015. During five years, she investigated how the gut flora (gut microbiome) of healthy infants develops in their first year of life.

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She specialized in the many aspects of microbiology and genomics, but also in bioinformatics and biostatistics.

Working experience

  • Trainee Patent Attorney, V.O. (2021-present)
  • PhD student, Rega Institute KU Leuven (2015-2021)

Education

  • PhD in Biomedical Sciences, KU Leuven (2020)
  • MSc in Biomedical Sciences, KU Leuven (2015)
  • BSc in Biomedical Sciences, KU Leuven (2013)

Publications

  • Conceição-Neto, N., Zeller, M., Lefrère, H., De Bruyn, P., Beller, L., Deboutte, W., Yinda, C. K., Lavigne, R., Maes, P., Ranst, M. Van, Heylen, E. & Matthijnssens, J. Modular approach to customise sample preparation procedures for viral metagenomics: A reproducible protocol for virome analysis. Sci. Rep. 5, 16532 (2015).
  • Yinda, C. K., Zeller, M., Conceição-Neto, N., Maes, P., Deboutte, W., Beller, L., Heylen, E., Ghogomu, S. M., Van Ranst, M. & Matthijnssens, J. Novel highly divergent reassortant bat rotaviruses in Cameroon, without evidence of zoonosis. Sci. Rep. 6, 34209 (2016).
  • Yinda, C. K., Ghogomu, S. M., Conceição-Neto, N., Beller, L., Deboutte, W., Vanhulle, E., Maes, P., Van Ranst, M. & Matthijnssens, J. Cameroonian fruit bats harbor divergent viruses, including rotavirus H, bastroviruses, and picobirnaviruses using an alternative genetic code. Virus Evol. 4, vey008 (2018).
  • Theuns, S., Vanmechelen, B., Bernaert, Q., Deboutte, W., Vandenhole, M., Beller, L., Matthijnssens, J., Maes, P. & Nauwynck, H. J. Nanopore sequencing as a revolutionary diagnostic tool for porcine viral enteric disease complexes identifies porcine kobuvirus as an important enteric virus. Sci. Rep. 8, 9830 (2018).
  • Vanmechelen, B., Bletsa, M., Laenen, L., Lopes, A. R., Vergote, V., Beller, L., Deboutte, W., Korva, M., Avšič Županc, T., Goüy de Bellocq, J., Gryseels, S., Leirs, H., Lemey, P., Vrancken, B. & Maes, P. Discovery and genome characterization of three new Jeilongviruses, a lineage of paramyxoviruses characterized by their unique membrane proteins. BMC Genomics 19, 617 (2018).
  • Yinda, C. K., Vanhulle, E., Conceição-Neto, N., Beller, L., Deboutte, W., Shi, C., Ghogomu, S. M., Maes, P., Van Ranst, M. & Matthijnssens, J. Gut Virome Analysis of Cameroonians Reveals High Diversity of Enteric Viruses, Including Potential Interspecies Transmitted Viruses. mSphere 4, (2019).
  • Beller, L. & Matthijnssens, J. What is (not) known about the dynamics of the human gut virome in health and disease. Curr. Opin. Virol. 37, 52–57 (2019).
  • Shi, C., Beller, L., Deboutte, W., Yinda, K. C., Delang, L., Vega-Rúa, A., Failloux, A.-B. & Matthijnssens, J. Stable distinct core eukaryotic viromes in different mosquito species from Guadeloupe, using single mosquito viral metagenomics. Microbiome 7, 121 (2019).
  • Wollants, E., Beller, L., Beuselinck, K., Bloemen, M., Lagrou, K., Reynders, M. & Van Ranst, M. A decade of enterovirus genetic diversity in Belgium. J. Clin. Virol. 121, 104205 (2019).
  • Deboutte, W., Beller, L., Yinda, C. K., Maes, P., de Graaf, D. C. & Matthijnssens, J. Honey-bee–associated prokaryotic viral communities reveal wide viral diversity and a profound metabolic coding potential. Proc. Natl. Acad. Sci. U. S. A. 117, 10511–10519 (2020).
  • Thijssen, M., Tacke, F., Beller, L., Deboutte, W., Yinda, K. C., Nevens, F., Laleman, W., Van Ranst, M. & Pourkarim, M. R. Clinical relevance of plasma virome dynamics in liver transplant recipients. EBioMedicine 60, 103009 (2020).
  • Simsek, C., Corman, V. M., Everling, H. U., Lukashev, A. N., Rasche, A., Maganga, G. D., Binger, T., Jansen, D., Beller, L., Deboutte, W., Gloza-Rausch, F., Seebens-Hoyer, A., Yordanov, S., Sylverken, A., Oppong, S., Sarkodie, Y. A., Vallo, P., Leroy, E. M., Bourgarel, M., Yinda, K. C., Van Ranst, M., Drosten, C., Drexler, J. F. & Matthijnssens, J. At least seven distinct rotavirus genotype constellations in bats with evidence of reassortment and zoonotic transmissions. MBio 12, (2021).

Languages

  • Dutch (native)
  • English (fluent)
  • French (basic)

 

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News

Put your hands together for the Nobel Prize in Chemistry 2021 – How fundamental research can lead to new opportunities in innovation

Last year the Nobel Prize in Chemistry goes to Benjamin List and David MacMillan for ‘the development of asymmetric organocatalysis’. This is a fine example of a fundamental scientific discovery that has quickly found a practical application.Continue reading

First meeting of the Administrative Committee of the new European Patent Court

On 22 February 2022, the first meeting of the Administrative Committee of the new European Patent Court (the Unified Patent Court) took place.Continue reading

Money Losing Party Court

V.O. model quickly estimates patent value

How do you estimate the economic value of a patent? V.O. has developed a model that arrives at an estimation based on various factors. This allows companies to have a better understanding of how much their patent can deliver for them.Continue reading

Events

Knowledge for Growth 2022

Gent ICC, Familie van Rysselberghedreef, Ghent, Belgium

The cream of the Belgian life sciences community attends flanders.bio’s annual knowledge for growth business conference, attracting decision makers from biotech, pharma and medtech, agricultural and chemical industry as well as investors, universities, topnotch research institutes, policymakers and competence providers. Continue reading

Dutch Lifes Sciences Conference 2022

CORPUS Congress Centre, Willem Einthovenstraat, Oegstgeest, Netherlands

The foremost life sciences business network event in the Netherlands. Continue reading

Unitary Patent Package Conference 2022

Van der Valk Hotel Amsterdam - Amstel, Joan Muyskenweg, Amsterdam, Netherlands

Finally the Unitary Patent and the Unified Patent Court will become reality! In January 2022 Austria ratified as the 13th country and the new system will be up and running in the second half of 2022. So, patent professionals get prepared! Continue reading