After studying Biomedical Sciences at KU Leuven, Leen started her PhD at the REGA institute of the KU Leuven in 2015. During five years, she investigated how the gut flora (gut microbiome) of healthy infants develops in their first year of life.
She specialized in the many aspects of microbiology and genomics, but also in bioinformatics and biostatistics.
Working experience
Trainee Patent Attorney, V.O. (2021-present)
PhD student, Rega Institute KU Leuven (2015-2021)
Education
PhD in Biomedical Sciences, KU Leuven (2020)
MSc in Biomedical Sciences, KU Leuven (2015)
BSc in Biomedical Sciences, KU Leuven (2013)
Publications
Conceição-Neto, N., Zeller, M., Lefrère, H., De Bruyn, P., Beller, L., Deboutte, W., Yinda, C. K., Lavigne, R., Maes, P., Ranst, M. Van, Heylen, E. & Matthijnssens, J. Modular approach to customise sample preparation procedures for viral metagenomics: A reproducible protocol for virome analysis. Sci. Rep. 5, 16532 (2015).
Yinda, C. K., Zeller, M., Conceição-Neto, N., Maes, P., Deboutte, W., Beller, L., Heylen, E., Ghogomu, S. M., Van Ranst, M. & Matthijnssens, J. Novel highly divergent reassortant bat rotaviruses in Cameroon, without evidence of zoonosis. Sci. Rep. 6, 34209 (2016).
Yinda, C. K., Ghogomu, S. M., Conceição-Neto, N., Beller, L., Deboutte, W., Vanhulle, E., Maes, P., Van Ranst, M. & Matthijnssens, J. Cameroonian fruit bats harbor divergent viruses, including rotavirus H, bastroviruses, and picobirnaviruses using an alternative genetic code. Virus Evol. 4, vey008 (2018).
Theuns, S., Vanmechelen, B., Bernaert, Q., Deboutte, W., Vandenhole, M., Beller, L., Matthijnssens, J., Maes, P. & Nauwynck, H. J. Nanopore sequencing as a revolutionary diagnostic tool for porcine viral enteric disease complexes identifies porcine kobuvirus as an important enteric virus. Sci. Rep. 8, 9830 (2018).
Vanmechelen, B., Bletsa, M., Laenen, L., Lopes, A. R., Vergote, V., Beller, L., Deboutte, W., Korva, M., Avšič Županc, T., Goüy de Bellocq, J., Gryseels, S., Leirs, H., Lemey, P., Vrancken, B. & Maes, P. Discovery and genome characterization of three new Jeilongviruses, a lineage of paramyxoviruses characterized by their unique membrane proteins. BMC Genomics 19, 617 (2018).
Yinda, C. K., Vanhulle, E., Conceição-Neto, N., Beller, L., Deboutte, W., Shi, C., Ghogomu, S. M., Maes, P., Van Ranst, M. & Matthijnssens, J. Gut Virome Analysis of Cameroonians Reveals High Diversity of Enteric Viruses, Including Potential Interspecies Transmitted Viruses. mSphere 4, (2019).
Beller, L. & Matthijnssens, J. What is (not) known about the dynamics of the human gut virome in health and disease. Curr. Opin. Virol. 37, 52–57 (2019).
Shi, C., Beller, L., Deboutte, W., Yinda, K. C., Delang, L., Vega-Rúa, A., Failloux, A.-B. & Matthijnssens, J. Stable distinct core eukaryotic viromes in different mosquito species from Guadeloupe, using single mosquito viral metagenomics. Microbiome 7, 121 (2019).
Wollants, E., Beller, L., Beuselinck, K., Bloemen, M., Lagrou, K., Reynders, M. & Van Ranst, M. A decade of enterovirus genetic diversity in Belgium. J. Clin. Virol. 121, 104205 (2019).
Deboutte, W., Beller, L., Yinda, C. K., Maes, P., de Graaf, D. C. & Matthijnssens, J. Honey-bee–associated prokaryotic viral communities reveal wide viral diversity and a profound metabolic coding potential. Proc. Natl. Acad. Sci. U. S. A. 117, 10511–10519 (2020).
Thijssen, M., Tacke, F., Beller, L., Deboutte, W., Yinda, K. C., Nevens, F., Laleman, W., Van Ranst, M. & Pourkarim, M. R. Clinical relevance of plasma virome dynamics in liver transplant recipients. EBioMedicine 60, 103009 (2020).
Simsek, C., Corman, V. M., Everling, H. U., Lukashev, A. N., Rasche, A., Maganga, G. D., Binger, T., Jansen, D., Beller, L., Deboutte, W., Gloza-Rausch, F., Seebens-Hoyer, A., Yordanov, S., Sylverken, A., Oppong, S., Sarkodie, Y. A., Vallo, P., Leroy, E. M., Bourgarel, M., Yinda, K. C., Van Ranst, M., Drosten, C., Drexler, J. F. & Matthijnssens, J. At least seven distinct rotavirus genotype constellations in bats with evidence of reassortment and zoonotic transmissions. MBio 12, (2021).
We are again proud of our recent recognitions by IP STARS (Managing IP) as a Tier 1 firm and for Belgium as a Tier 2 firm. And a Tier 3 listing for Trademark Prosecution. Individual recommendations as ‘IP Stars 2024’ are for Tamara Elmore, Bettina Hermann, Annemie Jaeken, Leo Jessen, Bernard Ledeboer, Marco Molling, Otto […]Continue reading
In the recently published JUVE Patent Netherlands ranking 2024, our firm once again receives a very prominent place. This ranking was compiled after a thorough survey of all leading Dutch patent firms, patent attorneys and litigators.Continue reading
We are starting again brand new versions of the two IE courses Basic and Advanced under the name IP Academy. The Basic course is scheduled on November 5 and the Advanced course on December 10, 2024.Continue reading
Hangzhou International Expo Center, Benjing 2nd Road, Xiaoshan District, Hangzhou, Zhejiang, China
The annual AIPPI Wereldcongres, held in September or October, is the one moment in the year when members from all around the world come together to discuss hot topics in Intellectual Property. Usually, up to 2000 members attend with accompanying persons.
For innovative entrepreneurs who wish to improve their intellectual property (IP) know-how, V.O. organizes a basic course on IP on Tuesday 5 November 2024 and an advanced course on Tuesday 10 December 2024. These courses will be given, in English, by our attorneys and feature many practical examples and skill trainings. Continue reading
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